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EU REACH

QSAR1)Predictions generated by differentsoftware, both commercial and freeware2)Customized model developmentaccording the requirement of client3)Assessment of each predictionreliability, as required by OECD principles for the validation, for regulatoryp…

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EU PPP

In all cases of new/increasedlevels of impurities, need:toxicology (Q)SAR analysis, if areliable prediction is possible and can be supported scientifically. If there is an SAR alert for theimpurity, it should be considered if this alert is also present in

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Mexico Pesticide Registration

When new impurities whose concentration is ≥0.1% (1g / kg), their non-relevance should be justified by QSAR.

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Brazil Pesticide Registration

In all cases of new impurities or enhanced levels of impurities are required studies of structure-activity relationship, covering all endpoints required for the evaluation of a technical product using different expert systems, and support data to explain

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Taiwan Pesticide Registration

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China New Chemical Substance Notifications

In the case where tests cannot be performed, internationally accepted estimation methods such as Quantitative Structure-Activity Relationships (QSAR) and read-across can be adopted.

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